Mycophenolate mofetil

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Gene mutation increases drug toxicity, rejection risk in pediatric kidney transplantsScreening for mutations in a gene that helps the body metabolize a kidney transplant anti-rejection drug may predict which children are at higher risk for side effects, including compromised white blood cell count or organ rejection, according to new research.Possibly related posts: (automatically generated)Endogenous Activators of TRPV1 and Gut Inflammation September 4, 2009 – We learn that today, Novartis Pharmaceuticals Corporation notified healthcare professionals that cases of Pure Red Cell Aplasia (PRCA) have been reported in patients treated with Mycophenolic acid [ Myfortic]. The WARNINGS and ADVERSE REACTIONS sections of the Mycophenolic acid [ ...

Author: medvidblog
Keywords: kidney transplantation allograft renal transplant transplants pediatrics
Added: April 13, 2009

Mycophenolate mofetil is usually given at a fixed-dose post-transplant, with dose reductions made only for toxicity. This is the third randomized-controlled trial to assess a strategy of dose adjustment based on drug levels. Concentration-controlled MMF combined with lower-dose calcineurin inhibitor ...

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